Lv45
800 积分 2025-01-15 加入
Compound EGFR mutations are predominantly PACC (P-loop and alpha-C helix compressing) mutations with increased responsiveness to second- vs third-generation tyrosine kinase inhibitors
4天前
已完结
Treatment of chronic obstructive pulmonary disease: current pipeline and new opportunities
9天前
已完结
A renaissance in targeting the PI3K/AKT/mTOR pathway
13天前
已完结
Contemporary design of small-molecule kinase modulators: orthosteric, allosteric and induced-proximity strategies
16天前
已完结
Brain penetration enhancer-based on amino acid prodrug self-assembling nanoparticles: a streamlined strategy for overcoming blood brain barrier
16天前
已完结
A small molecule PTER-selective inhibitor reduces food intake and body weight
21天前
已完结
Enantioselective Intramolecular Cyclopropanations of Allylic and Homoallylic Diazoacetates and Diazoacetamides Using Chiral Dirhodium(II) Carboxamide Catalysts
26天前
已完结
Discovery of the Orally Bioavailable Isoform Selective Janus Kinase 1 (JAK1) Compound Povorcitinib (INCB054707) for the Treatment of Inflammatory and Autoimmune Diseases
28天前
已完结
721 - Efficacy and safety of povorcitinib for extensive vitiligo: 52-week results from a double-blinded, placebo-controlled, dose-ranging phase 2b study
28天前
已完结
Lessons learned in linking PROTACs from discovery to the clinic
28天前
已完结
皖公网安备34019202002308
