Lv11
22 积分 2022-05-12 加入
Senescence-related gene signature predicts prostate cancer progression and identifies PCNA as a therapeutic target via multi-omics machine learning integration
19分钟前
待确认
Second-Generation AOH1996 Analogues with Enhanced Pharmacological Properties for Targeting PCNA
37分钟前
求助中
Selective Metalation of Functionalized Quinazolines to Enable Discovery and Advancement of Covalent KRAS Inhibitors
29天前
已完结
Process Development of the Pyrazinecarboxamide Component of Gilteritinib, a FLT3 Inhibitor
1个月前
已完结
Targeting Cancer-Associated PCNA with AOH1996 Induces Mitotic Catastrophe and Enhances Cisplatin Therapy in Cervical Cancer
2个月前
已完结
Design and Development of DNA Damage Chemical Inducers of Proximity for Targeted Cancer Therapy
5个月前
已完结
Abstract 4580: Novel PCNA inhibitor AOH1996 synergizes with KRAS-targeted therapies in pancreatic ductal adenocarcinoma
5个月前
已完结
JYP0322, a highly selective and brain-penetrant ROS1 inhibitor, overcomes ROS1 resistance mutation in NSCLC: The first-in-human phase 1 trial
5个月前
已关闭
Abstract 5791: Preclinical characterization of NEO-811, a novel molecular glue degrader of ARNT for the treatment of clear cell renal cell carcinoma
5个月前
已关闭
The Myeloma Drug Lenalidomide Promotes the Cereblon-Dependent Destruction of Ikaros Proteins
5个月前
已完结