Lv5
830 积分 2022-08-16 加入
Discovery of the Clinical Candidate IDOR-1117-2520: A Potent and Selective Antagonist of CCR6 for Autoimmune Diseases
1个月前
已完结
Discovery of PF-07054894, a Potent Squaramide-Based CCR6 Antagonist Displaying High CXCR2 Selectivity
1个月前
已完结
Discovery of AZD4144, a Selective and Potent NLRP3 Inhibitor for the Treatment of Inflammatory Diseases
1个月前
已完结
Discovery of novel triazolobenzazepinones as γ-secretase modulators with central Aβ42 lowering in rodents and rhesus monkeys
2个月前
已完结
Organocatalytic Reductive Amination of Aldehydes with 2-Propanol: Efficient Access to N-Alkylated Amines
3个月前
已完结
Aminative Suzuki–Miyaura coupling
6个月前
已完结
Facile N-Cbz cleavage by stoichiometric sulfonic acid in HFIP
8个月前
已完结
Discovery of Pyrrolopyrazine Carboxamide Derivatives as Potent and Selective FGFR2/3 Inhibitors that Overcome Mutant Resistance
9个月前
已完结
Discovery of WRN inhibitor HRO761 with synthetic lethality in MSI cancers
1年前
已完结
Chemoproteomic discovery of a covalent allosteric inhibitor of WRN helicase
1年前
已完结
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