Lv5
1210 积分 2022-08-24 加入
The CDK inhibitor CR8 acts as a molecular glue degrader that depletes cyclin K
10天前
已完结
Covalent targeting of remote cysteine residues to develop CDK12 and CDK13 inhibitors
11天前
已完结
Discovery of Highly Potent and Orally Available CCNK Molecular Glue Degraders as Broad-Spectrum Antitumor Agents
11天前
已完结
AI-Powered Virtual Screening of Large Compound Libraries Leads to the Discovery of Novel Inhibitors of Sirtuin-1
29天前
已完结
MEG-mod: A Multiview Enhanced Graph Neural Network for Knockdown Efficiency Prediction of Chemically Modified siRNA
1个月前
已完结
The Medicinal Chemistry and Therapeutic Potential of LRH-1 Modulators
1个月前
已完结
Discovery Process of Enlicitide, a Highly Engineered Macrocyclic Peptide Therapeutic, through Issue-Driven Fragment-Based Synthetic Assembly and SAR
1个月前
已完结
Chemoproteomic development of SLC15A4 inhibitors with anti-inflammatory activity
1个月前
已完结
Discovery of novel indole derivatives as LRH-1 antagonists for the treatment of castration resistant prostate cancer
1个月前
已完结
Identification of Small Molecule Agonists of the Orphan Nuclear Receptors Liver Receptor Homolog-1 and Steroidogenic Factor-1
1个月前
已完结
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