Lv52
1510 积分 2022-08-24 加入
Discovery of Novel Allosteric EGFR L858R Inhibitors for the Treatment of Non-Small-Cell Lung Cancer as a Single Agent or in Combination with Osimertinib
7天前
已完结
Novel Carboxamide-Based Allosteric MEK Inhibitors: Discovery and Optimization Efforts toward XL518 (GDC-0973)
13天前
已完结
Overcoming EGFR(T790M) and EGFR(C797S) resistance with mutant-selective allosteric inhibitors
13天前
已完结
Extracellular targeted protein degradation: an emerging modality for drug discovery
13天前
已完结
QComp: A QSAR-Based Imputation Framework for Drug Discovery
21天前
已完结
Molecular glues that facilitate RAS binding to PI3Kα promote glucose uptake without insulin
21天前
已完结
CLaSP: A Contrastive Learning-Guided Latent Scoring Platform for Comprehensive Drug-Likeness Evaluation
22天前
已完结
Steuerung der intrazellulären Proteinmenge durch niedermolekulare Modulatoren des Ubiquitin‐Proteasom‐Systems
25天前
已完结
Small‐Molecule‐Mediated Degradation of the Androgen Receptor through Hydrophobic Tagging
25天前
已完结
Small-molecule hydrophobic tagging–induced degradation of HaloTag fusion proteins
25天前
已完结
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