Lv5
1500 积分 2022-08-24 加入
Potent and selective Bruton's tyrosine kinase inhibitors: Discovery of GDC-0834
14天前
已完结
The Discovery of Bridged Benzoazepine Amides as Selective Allosteric Modulators of RIPK1
21天前
已完结
Simple Predictive Models of Passive Membrane Permeability Incorporating Size-Dependent Membrane-Water Partition
2个月前
已完结
Utilizing structure based drug design and metabolic soft spot identification to optimize the in vitro potency and in vivo pharmacokinetic properties leading to the discovery of novel reversible Bruton’s tyrosine kinase inhibitors
2个月前
已完结
Next-Generation Anti-IL-17 Agents for Psoriatic Disease: A Pipeline Review
2个月前
已完结
Ultradeep Phosphoproteomics for Assessing Protein Kinase Inhibitor Selectivity on a Proteome Scale
2个月前
已完结
Discovery of structural diverse reversible BTK inhibitors utilized to develop a novel in vivo CD69 and CD86 PK/PD mouse model
2个月前
已完结
Discovery and Preclinical Characterization of BIIB091, a Reversible, Selective BTK Inhibitor for the Treatment of Multiple Sclerosis
2个月前
已完结
Large Language Models as Tools for Molecular Toxicity Prediction: AI Insights into Cardiotoxicity
2个月前
已完结
AI-Augmented R-Group Exploration in Medicinal Chemistry
2个月前
已完结
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