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20 积分 2026-07-08 加入
Emerging degrader technologies engaging lysosomal pathways
1个月前
已完结
Critical assessment of LC3/GABARAP ligands used for degrader development and ligandability of LC3/GABARAP binding pockets
1个月前
已完结
Development of Degraders of Cyclin-Dependent Kinases 4 and 6 Based on Rational Drug Design
1个月前
已完结
Development of Dual and Selective Degraders of Cyclin‐Dependent Kinases 4 and 6
1个月前
已完结
PROTAC-mediated CDK degradation differentially impacts cancer cell cycles due to heterogeneity in kinase dependencies
1个月前
已完结
Navigating first- and second-line treatment options in HR+HER2-negative advanced breast cancer
1个月前
已完结
MKRN2-Mediated Degradation of IGF2BP3 Suppresses MYC and Enhances CDK4/6 Inhibitor Sensitivity in Bladder Cancer
1个月前
已完结
Developing Orally Active Estrogen Receptor Degraders by Conjugation of Boronic Tamoxifen and Cereblon Ligands
1个月前
已完结
CDK4/6-targeted therapy: From clinical inhibitors to emerging strategies to overcome resistance
1个月前
已完结
Autophagic degradation of CDK4 is responsible for G0/G1 cell cycle arrest in NVP-BEZ235-treated neuroblastoma
1个月前
已完结
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