Lv31
216 积分 2025-09-22 加入
A first-in-class RNA degrader reduces c-MYC expression and myeloma cell survival in preclinical models
8小时前
待确认
GID4-Recruiting PROTACs for BRD4 Degradation Overcome Resistance Driven by CRBN and VHL Deficiency
26天前
已完结
Degron-independent recruitment of KAT2A expands the target space of CRBN molecular glues
1个月前
已完结
Targeted Degradation of ZBP1 with Covalent PROTACs for Anti-Inflammatory Treatment of Infections
1个月前
已完结
Flourishing innovation in KRAS targeting: Recent advances in medicinal chemistry strategies and future perspectives
1个月前
已完结
Phase separation–based HTS identifies cobimetinib as a YAP-TEAD inhibitor that suppresses hyperactivated YAP-induced cancer progression
1个月前
已完结
Pharmacological targeting of IRF4 as a therapeutic strategy for multiple myeloma
2个月前
已完结
KRAShing pancreatic cancer before takeoff
2个月前
已完结
A peptide-centric local stability assay enables proteome-scale identification of the protein targets and binding regions of diverse ligands
2个月前
已完结
Hsp70-Targeting Chimeras Enable Dual Proteasomal and Lysosomal Degradation of Intracellular and Extracellular Proteins
2个月前
已完结