Lv2
120 积分 2025-09-22 加入
Design of PROTACs utilizing the E3 ligase GID4 for targeted protein degradation
18天前
已完结
Structure-based design and synthesis of novel highly potent and selective KRASG12C inhibitors
21天前
已完结
Ca2+-driven E3 ligase activity
23天前
已关闭
Chemical acylation of an acquired serine suppresses oncogenic signaling of K-Ras(G12S)
24天前
已完结
New promises and challenges in the treatment of advanced non-small-cell lung cancer
1个月前
已完结
Tumor-Selective Gene Therapy: Using Hairpin DNA Oligonucleotides to Trigger Cleavage of Target RNA by Endogenous flap endonuclease 1 (FEN 1) Highly Expressed in Tumor Cells
2个月前
已完结
Degrons and degradation signals beyond short linear motifs
3个月前
已完结
Co-opting the E3 ligase KLHDC2 for targeted protein degradation by small molecules
3个月前
已完结
NCOA4 linked to endothelial cell ferritinophagy and ferroptosis:a key regulator aggravate aortic endothelial inflammation and atherosclerosis
3个月前
已完结
Mining the CRBN target space redefines rules for molecular glue-induced neosubstrate recognition
3个月前
已完结
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