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210 积分 2025-04-14 加入
Regorafenib enhances anti-PDCD1/PD-1 therapeutic efficacy in colorectal cancer by promoting SQSTM1/p62-mediated CD274/PD-L1 degradation
4天前
已完结
The MEK–RAF molecular glue IK-595 has potent antitumor activity across RAS/MAPK pathway-altered cancers
1个月前
已完结
Lessons learned in linking PROTACs from discovery to the clinic
1个月前
已完结
Chemical tools for the Gid4 subunit of the human E3 ligase C-terminal to LisH (CTLH) degradation complex
2个月前
已完结
A rapid chemical reprogramming system to generate human pluripotent stem cells
2个月前
已完结
A chemical probe to modulate human GID4 Pro/N-degron interactions
2个月前
已完结
The expanding repertoire of covalent warheads for drug discovery
3个月前
已完结
求助论文《The design and development of LRRK2 inhibitors as novel therapeutics for Parkinson's disease》
5个月前
已完结
Artificial intelligence in drug development
6个月前
已完结
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