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1910 积分 2025-04-09 加入
PROteolysis TArgeting Chimeras (PROTACs) and beyond: targeted degradation as a new path to fight microbial pathogens
10天前
已关闭
Extracellular targeted protein degradation: an emerging modality for drug discovery
10天前
已完结
Targeted protein degradation: from mechanisms to clinic
10天前
已完结
Discovery of Covalent MLKL PROTAC Degraders via Optimization of a Theophylline Derivative Ligand for Treating Necroptosis
10天前
已完结
MG132, a proteasome inhibitor, induces apoptosis in tumor cells
12天前
已完结
Inhibiting intracellular CD28 in cancer cells enhances antitumor immunity and overcomes anti-PD-1 resistance via targeting PD-L1
13天前
已完结
Targeting tumor-infiltrating regulatory T cells: combining CD47 and PD-L1 inhibition via a novel aptamer-siRNA chimera
13天前
已完结
Advancing targeted protein degradation for cancer therapy
14天前
已完结
A Role for the Cyclin Box in the Ubiquitin-Mediated Degradation of Cyclin G1
17天前
已关闭
First-in-Class Quinoline-Dione-Derived PROTACs: Potent Degraders of Cdc25 Phosphatases for Antitumor Therapy
21天前
已完结
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