Lv62
3090 积分 2023-09-20 加入
Design, Synthesis, and Structure−Activity Relationships of Thieno[2,3-b]pyridin-4-one Derivatives as a Novel Class of Potent, Orally Active, Non-Peptide Luteinizing Hormone-Releasing Hormone Receptor Antagonists
20天前
已完结
Targeted inhibition of menin promotes β‐catenin‐mediated GLP ‐1 expression and improves glucose tolerance in high‐fat diet‐induced obese mice
1个月前
已完结
Design of Potent Menin–KMT2A Interaction Inhibitors with Improved In Vitro ADME Properties and Reduced hERG Affinity
1个月前
已完结
Menin-MLL protein-protein interaction inhibitors: a patent review (2014–2021)
1个月前
已完结
Menin-MLL protein–protein interaction inhibitors: a patent review (2021-present)
1个月前
已完结
The role of menin inhibitors in acute myeloid leukemia
1个月前
已关闭
RIPTACs expand anticancer target space
1个月前
已完结
Induced proximity pushes beyond protein degraders, as first RIPTAC moves into the clinic
1个月前
已完结
Discovery of Selective Histone Deacetylase 1 and 2 Inhibitors: Screening of a Focused Library Constructed by Click Chemistry, Kinetic Binding Analysis, and Biological Evaluation
4个月前
已完结