Lv7
4120 积分 2023-08-18 加入
Identification of Clofibric Acid as a Synoviolin (SYVN1) Ligand for Proteolysis-Targeting Chimera (PROTAC) Development
2小时前
已完结
Drug Delivery Strategy Exploiting Amino Acid Prodrugs: Improving Oral Bioavailability and Overcoming Nonlinear Pharmacokinetic Challenges Following Dose Escalation of a CK2 Inhibitor with Poor Solubility
2小时前
已完结
Discovery of Schiff base-triazole-pleuromutilin conjugates as broad-spectrum antibacterial agents with potent anti-MRSA activity
4天前
已完结
From Virtual Screening to Reality: Identifying Potent PI3Kγ Inhibitors for Inflammation Treatment by Harnessing Machine Learning and Biological Validation
4天前
已完结
New N-(isoxazol-3-yl)-4-(1,3,4-thiadiazol-3(2H)-yl)benzenesulfonamide derivatives as potent Aurora kinases inhibitors: Design, synthesis and anti-proliferative activity
4天前
已完结
Green synthesis of biscoumarin derivatives as anti-psoriatic agents targeting PI3K/AKT/JAK2 signaling pathways
4天前
已完结
A homologous cell membrane-coated peptide-based USP7 degrader enhances degradation efficiency and anti-tumor activity in gastric Cancer
4天前
已完结
Identification of a nanomolar, selective MAO-B inhibitor from piperidine-based chalcones with anti-Parkinson potential
4天前
已完结
A rapid and scalable microwave-assisted strategy for the synthesis of neocryptolepine and its analogues: Comprehensive bioactivity profiling
4天前
已完结
Discovery of novel imidazo[2,1-b]thiazole-hydrazone hybrids as multi-target anticancer agents: Dual PARP-1/COX-2 inhibition and MetAP-2 modulation
6天前
已完结