Lv7
3710 积分 2023-08-18 加入
Lead Optimization of Multimutant KRAS Switch-II Pocket Macrocyclic Inhibitors via Isosteric Replacement to Improve ADME and Oral Exposure
1小时前
待确认
A Novel Trigonal Prismatic Rhenium Complex of 2-Hydroxythiobenzhydrazide as a Potent and Selective Anticancer Agent
1小时前
已完结
Discovery of a Highly Promising Disulfide Derivative Scaffold as Inhibitor of SARS‐CoV‐2 Main Protease
15天前
已完结
Multifunctional quinoline-based hydrazones as promising antidiabetic agents: experimental and computational insights
19天前
已完结
Design, synthesis and preliminary evaluation of mosquitoicidal activity of arecoline derivatives targeting muscarinic acetylcholine receptors
19天前
已完结
Combined antitumor efficacy of a new tanshinone IIA analog and irinotecan with alleviating gastrointestinal side effect
19天前
已完结
Ligand-based design and synthesis of novel 3-spiro-2-oxindoline derivatives as potent VEGFR-2 inhibitors with antiproliferative activity and cell cycle arrest
19天前
已完结
Design and synthesis of novel thiazolotriazole–sulfonamide hybrids tackling antimicrobial resistance: mechanistic insights into efflux pump inhibitor, gene downregulation, and machine-aided results
19天前
已完结
Development of novel diaryl ether–phenolic Mannich Base derivatives with potent cholinesterase inhibition and low neuronal toxicity
19天前
已完结
Design of fluorinated triazinoindoles as highly potent and markedly selective ALR2 inhibitors: synthesis, in silico and in vitro evaluation of promising lead compounds
19天前
已完结
皖公网安备34019202002308
