Lv2
122 积分 2022-05-24 加入
Discovery of Highly Potent and Selective Thyroid Hormone Receptor β Agonists for the Treatment of Nonalcoholic Steatohepatitis
1个月前
已完结
Eucalyptus globulus fruit extract alleviates MASLD via modulation of the IRE1α/XBP1s pathway
1个月前
已完结
A fluorescence-based high-content imaging workflow for multi-parametric lipid droplet phenotyping via Oil Red O fluorescence
3个月前
已完结
Cryo-EM structures of GPR75 reveal an occluded orthosteric pocket challenging conventional drug discovery paradigms for an anti-obesity target
3个月前
已完结
G protein-coupled receptor 75 mediates depression-like behaviors and HPA axis hyperactivity through an excitatory arcuate-paraventricular nucleus circuit
3个月前
已完结
Current status and future trends of the global burden of MASLD
3个月前
已完结
The Sigma-1 Receptor as a Pluripotent Modulator in Living Systems
3个月前
已完结
SIRT3-mediated mitophagy by deacetylating ATP5F1A involved in the protective effects of SIGMAR1/Sigma-1 receptor against ferroptosis and microvascular hyperpermeability in lipopolysaccharide-induced acute lung injury
3个月前
已完结
Cannabinoid receptor 1 ligands: Biased signaling mechanisms driving functionally selective drug discovery
4个月前
已完结
Discovery of a σ1 receptor antagonist by combination of unbiased cell painting and thermal proteome profiling
5个月前
已完结