Lv11
50 积分 2023-11-01 加入
Discovery and Characterization of the Topical Soft JAK Inhibitor CEE321 for Atopic Dermatitis
12天前
已完结
Discovery of a Novel Potent and Selective HSD17B13 Inhibitor, BI-3231, a Well-Characterized Chemical Probe Available for Open Science
12天前
已完结
Design, Synthesis, and Biological Evaluation of Androgen Receptor (AR) Antagonist-Heat Shock Protein 90 (Hsp90) Inhibitor Conjugates for Targeted Therapy of Castration-Resistant Prostate Cancer
12天前
已完结
A Molecular Toolbox of Positron Emission Tomography Tracers for General Anesthesia Mechanism Research
12天前
已完结
Stereochemical Control of Splice Modulation in FD-895 Analogues
12天前
已完结
Discovery of an Oral, Beyond-Rule-of-Five Mcl-1 Protein–Protein Interaction Modulator with the Potential of Treating Hematological Malignancies
12天前
已完结
First-in-Class Selective Inhibitors of the Lysine Acetyltransferase KAT8
12天前
已完结
Structural Modification and Pharmacological Evaluation of Substituted Quinoline-5,8-diones as Potent NSD2 Inhibitors
12天前
已完结
Discovery of a Series of Substituted 1H-((1,2,3-Triazol-4-yl)methoxy)pyrimidines as Brain Penetrants and Potent GluN2B-Selective Negative Allosteric Modulators
12天前
已完结
Designing Tailored Thiosemicarbazones with Bespoke Properties: The Styrene Moiety Imparts Potent Activity, Inhibits Heme Center Oxidation, and Results in a Novel “Stealth Zinc(II) Complex”
12天前
已完结