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68 积分 2023-06-24 加入
Antitumor Polycyclic Acridines. 17. Synthesis and Pharmaceutical Profiles of Pentacyclic Acridinium Salts Designed To Destabilize Telomeric Integrity
13天前
已完结
Discovery of Novel 2,4,5-Trisubstituted Pyrimidine Derivatives as Potent and Selective FGFR Inhibitors against Gatekeeper Mutants for the Treatment of NSCLC
1个月前
已完结
Design, synthesis and antitumor activity of a novel FGFR2-selective degrader to overcome resistance of the FGFR2V564F gatekeeper mutation based on a pan-FGFR inhibitor
2个月前
已完结
Drug-induced enzyme activity inhibition and CYP3A4 genetic polymorphism significantly shape the metabolic characteristics of furmonertinib
4个月前
已完结
Triptolide inhibits intrahepatic cholangiocarcinoma growth by suppressing glycolysis via the AKT/mTOR pathway
4个月前
已完结
Activity Variations of CYP2B6 Determine the Metabolic Stratification of Efavirenz
5个月前
已完结
Identification of Pyridinyltriazine Derivatives as Potent panFGFR Inhibitors against Gatekeeper Mutants for Overcoming Drug Resistance
5个月前
已完结
EXPRESSION, PURIFICATION, AND CHARACTERIZATION OF MOUSE CYP2D22
5个月前
已完结
The impact of CYP3A4 genetic polymorphism on crizotinib metabolism and drug-drug interactions
7个月前
已完结
ABCB1 and ABCG2 limit brain penetration and, together with CYP3A4, total plasma exposure of abemaciclib and its active metabolites
7个月前
已完结
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