Lv2
200 积分 2021-10-28 加入
Molecular glues that facilitate RAS binding to PI3Kα promote glucose uptake without insulin
13天前
已完结
Targeted protein degradation: from mechanisms to clinic
14天前
已完结
Phase 2 Trial of Iberdomide in Systemic Lupus Erythematosus
14天前
已完结
Identification of a Primary Target of Thalidomide Teratogenicity
14天前
已完结
Mining the CRBN target space redefines rules for molecular glue–induced neosubstrate recognition
16天前
已完结
The Myeloma Drug Lenalidomide Promotes the Cereblon-Dependent Destruction of Ikaros Proteins
16天前
已完结
Structure of the human Cereblon–DDB1–lenalidomide complex reveals basis for responsiveness to thalidomide analogs
16天前
已完结
Design, synthesis and biological evaluation of novel quinazolinone derivatives as CRBN E3 ligase modulators
17天前
已完结
Iberdomide plus dexamethasone in heavily pretreated late-line relapsed or refractory multiple myeloma (CC-220-MM-001): a multicentre, multicohort, open-label, phase 1/2 trial
17天前
已完结
NX-2127-001, a First-in-Human Trial of NX-2127, a Bruton's Tyrosine Kinase-Targeted Protein Degrader, in Patients with Relapsed or Refractory Chronic Lymphocytic Leukemia and B-Cell Malignancies
17天前
已完结
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