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48 积分 2026-04-16 加入
The immune contexture in human tumours: impact on clinical outcome
20小时前
已完结
Sphingosine kinase 2 as a metabolic immune checkpoint in hepatocellular carcinoma: linking lipid metabolism and tumor immune escape
3天前
已关闭
Sphingosine kinase 2 drives immunosuppressive myeloid cell function via S1P-ACC1-dependent phosphatidylcholine metabolism to limit anti-PD1 responsiveness
3天前
已关闭
Palmitate-induced mitochondrial damage restricts histone acetylation in CD8 T cells to impair antitumor immunity
3天前
已完结
Study on the synthesis, characterization, and antitumor mechanism investigation of QZQ-01115 via targeting sphingosine kinase 2
1个月前
已完结
Revealing 2-dimethylhydrazino-2-alkyl alkynyl sphingosine derivatives as sphingosine kinase 2 inhibitors: Some hints on the structural basis for selective inhibition
2个月前
已完结
Electrochemical Indole Skeletal Editing via Single-Carbon Atom Insertion
3个月前
已完结
Skeletal Editing of Aromatic N‐Heterocycles via Hydroborative Cleavage of C−N Bonds—Scope, Mechanism, and Property
3个月前
已完结
Novel Sphingosine Kinase 1 Inhibitor Suppresses Growth of Solid Tumor and Inhibits the Lung Metastasis of Triple-Negative Breast Cancer
3个月前
已完结
Design, synthesis, antitumor activity, and molecular dynamics simulations of novel sphingosine kinase 2 inhibitors
3个月前
已完结