spencerleo
Lv1
20 积分
2023-03-08 加入
-
Discovery of Potent and Selective Methylenephosphonic Acid CD73 Inhibitors
9天前
已完结
-
Macrocycles and macrocyclization in anticancer drug discovery: Important pieces of the puzzle
10天前
已完结
-
An updated patent review of anaplastic lymphoma kinase inhibitors (2018–2022)
13天前
已完结
-
Discovery of (10R)-7-Amino-12-fluoro-2,10,16-trimethyl-15-oxo-10,15,16,17-tetrahydro-2H-8,4-(metheno)pyrazolo[4,3-h][2,5,11]-benzoxadiazacyclotetradecine-3-carbonitrile (PF-06463922), a Macrocyclic Inhibitor of Anaplastic Lymphoma Kinase (ALK) and c-ros Oncogene 1 (ROS1) with Preclinical Brain Exposure and Broad-Spectrum Potency against ALK-Resistant Mutations
14天前
已完结
-
Analysis of lorlatinib analogs reveals a roadmap for targeting diverse compound resistance mutations in ALK-positive lung cancer
15天前
已完结
-
The landscape of small-molecule prodrugs
19天前
已完结
-
Recent advances in the development of dual ALK/ROS1 inhibitors for non-small cell lung cancer therapy
20天前
已完结
-
Recent Updates on Structural Aspects of ALK Inhibitors as an Anticancer Agent
20天前
已完结
-
Linker Substitution Influences Succinimide Ring Hydrolysis Equilibrium Impacting Stability of Attachment to the Antibody-Drug Conjugate
24天前
已完结
-
ez-ADiCon: A novel glyco-remodeling based strategy that enables preparation of homogenous antibody-drug conjugates via one-step enzymatic transglycosylation with payload-preloaded bi-antennary glycan complexes
29天前
已完结