Lv11
40 积分 2023-03-08 加入
Discovery of Potent, Dual-Inhibitors of Diacylglycerol Kinases Alpha and Zeta Guided by Phenotypic Optimization
5小时前
待确认
Optimization of a series of novel, potent and selective Macrocyclic SYK inhibitors
1个月前
已完结
Design and Synthesis of Pyrazole-Based Macrocyclic Kinase Inhibitors Targeting BMPR2
1个月前
已完结
Structure-Based Optimization of Pyrazinamide-Containing Macrocyclic Derivatives as Fms-like Tyrosine Kinase 3 (FLT3) Inhibitors to Overcome Clinical Mutations
1个月前
已完结
Macrocyclization as a Source of Desired Polypharmacology. Discovery of Triple PI3K/mTOR/PIM Inhibitors
1个月前
已完结
Selective Macrocyclic Inhibitors of DYRK1A/B
1个月前
已完结
Accelerated Discovery of Macrocyclic CDK2 Inhibitor QR-6401 by Generative Models and Structure-Based Drug Design
1个月前
已完结
The Missing Link(er): A Roadmap to Macrocyclization in Drug Discovery
1个月前
已完结
The New Frontier: Merging Molecular Glue Degrader and Antibody–Drug Conjugate Modalities To Overcome Strategic Challenges
1个月前
已完结
The Discovery of RP-2119: A Potent, Selective, and Orally Bioavailable Polθ ATPase Inhibitor
1个月前
已完结
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