Lv3
400 积分 2025-11-17 加入
The application of mechanistic absorption, distribution, metabolism and excretion studies and physiologically-based pharmacokinetic modeling in the discovery of the next-generation oral selective estrogen receptor degrader camizestrant to achieve an acceptable human pharmacokinetic profile
1个月前
已关闭
N-myristoyltransferases: structure, function, disease, and inhibitors
1个月前
已完结
Ab initio calculations of the structural, electronic and mechanical properties of palygorskite under high pressure
1个月前
已完结
Development of a novel 18F-labeled radiotracer targeting granzyme B for imaging early tumor responses to immunotherapy
2个月前
已关闭
Cleavage of benzyl esters by diiodine–triethylsilane system
2个月前
已完结
Design of PROTACs utilizing the E3 ligase GID4 for targeted protein degradation
3个月前
已完结
Design of PROTACs utilizing the E3 ligase GID4 for targeted protein degradation
4个月前
已完结
Antibody-Drug Conjugates in Oncology: Why Potency Is No Longer the Limiting Factor
4个月前
已关闭
Covalent inhibitors of the RAS binding domain of PI3Kα impair tumor growth driven by RAS and HER2
4个月前
已完结
Autoimmune pathways in mice and humans are blocked by pharmacological stabilization of the TYK2 pseudokinase domain
5个月前
已完结
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