Lv31
300 积分 2024-09-23 加入
Discovery of APS03118, a Potent and Selective Next-Generation RET Inhibitor with a Novel Kinase Hinge Scaffold
3小时前
已完结
Integrating Multimodal AI with Encoded Medicinal Knowledge and Physics Simulations: A Unified Platform for Accelerated Drug Discovery from Patent Analysis to Potency Validation
4小时前
已完结
Discovery of TRAF-2 and NCK-interacting kinase (TNIK) inhibitors by ligand-based virtual screening methods
4天前
已完结
Soft drugs: design principles and topical applications
5天前
已完结
Metabolic and Pharmaceutical Aspects of Fluorinated Compounds
7天前
已完结
Discovery of Novel 2-(2-Benzimidazole)-Substituted Tetrahydrofur-ans as Potent and Selective NaV1.8 Inhibitors for the Treatment of Pain
18天前
已完结
Synthesis of the Substituted 7-Azaindazole Core of TEAD Inhibitor GDC-8025 via Gould–Jacobs Cyclization and Halogen Dance Routes
23天前
已完结
Rational Design of Covalent Kinase Inhibitors by an Integrated Computational Workflow (Kin-Cov)
24天前
已完结
TRI-611, a selective, brain-penetrant molecular glue degrader of ALK
28天前
已完结
A 2-in-1 Strategy for the Discovery of Compact HDAC8 Protac Degraders
1个月前
已完结
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