Lv21
196 积分 2024-08-21 加入
Discovery of 4-Aryl-5,6,7,8-tetrahydroisoquinolines as Potent, Selective, and Orally Active Aldosterone Synthase (CYP11B2) Inhibitors: In Vivo Evaluation in Rodents and Cynomolgus Monkeys
1个月前
已完结
Hypertension and Lorundrostat: Key Discoveries From the TARGET-HTN Trial
1个月前
已完结
Aldosterone Synthase Inhibition With Lorundrostat for Uncontrolled Hypertension
1个月前
已完结
Clinical Pharmacokinetics and Pharmacodynamics of Baxdrostat
1个月前
已完结
Evaluating phase II results of Baxdrostat, an aldosterone synthase inhibitor for hypertension
1个月前
已完结
Phase 2 Trial of Baxdrostat for Treatment-Resistant Hypertension
1个月前
已完结
OR09-6 Selective and Durable Suppression of Aldosterone Production in Non-Human Primates by a Novel Aldosterone Synthase Inhibitor
1个月前
已关闭
Novel Pyridyl Substituted 4,5-Dihydro-[1,2,4]triazolo[4,3-a]quinolines as Potent and Selective Aldosterone Synthase Inhibitors with Improved in Vitro Metabolic Stability
1个月前
已完结
Discovery of selective CYP11B2 (aldosterone synthase) inhibitors for the therapy of congestive heart failure and myocardial fibrosis
1个月前
已完结
Heteroaryl-Substituted Naphthalenes and Structurally Modified Derivatives: Selective Inhibitors of CYP11B2 for the Treatment of Congestive Heart Failure and Myocardial Fibrosis
1个月前
已完结
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