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54 积分 2024-09-20 加入
Mesenchymal stromal cells confer breast cancer doxorubicin resistance by producing hyaluronan
1天前
已完结
The Potential of PARP Inhibitors as Antitumor Drugs and the Perspective of Molecular Design
1个月前
已完结
Beyond Target Occupancy in Triple-Negative Breast Cancer: A Medicinal Chemistry Perspective on Modality-Guided Design for Durable Network Control
1个月前
已完结
Discovery of 4-Hydroxyquinazoline Derivatives as Small Molecular BET/PARP1 Inhibitors That Induce Defective Homologous Recombination and Lead to Synthetic Lethality for Triple-Negative Breast Cancer Therapy
1个月前
已完结
Cyclin-Dependent Kinases 4 and 6 Inhibitors: An Emerging Therapeutic Framework from Growth Suppression to Tumor Clearance
1个月前
已完结
Novel Benzamide Derivatives with Indole Moiety as Dual-Target Antiviral Agents: Rational Design, Efficient Synthesis, and Potent Anti-Influenza Activity Through Concurrent Binding to PAC Terminal Domain and Viral Nucleoprotein
1个月前
已完结
Multi-target exploration of newly synthesized pyrazoline-quinoline derivatives via in vitro screening, QSAR, molecular docking, MD simulations, and DFT analysis
1个月前
已关闭
Discussion on the Influence of Gpx 4 Target in the Field of Cancer
1个月前
已完结
Triple combination targeting PI3K, ER, and CDK4/6 inhibits growth of ER‐positive breast cancer resistant to fulvestrant and CDK4/6 or PI3K inhibitor
1个月前
已完结
Structure–Activity Relationship Study of Indolin-5-yl-cyclopropanamine Derivatives as Selective Lysine Specific Demethylase 1 (LSD1) Inhibitors
1个月前
已完结