Lv2
110 积分 2025-04-24 加入
Rational design of Gi-biased CB1 agonist with reduced side effects
9天前
已完结
Stereoisomers of N-[1-(2-Hydroxy-2-phenylethyl)-3-methyl-4-piperidyl]- N-phenylpropanamide: Synthesis, Stereochemistry, Analgesic Activity, and Opioid Receptor Binding Characteristics
10天前
已完结
<p>APOLLO-1: a randomized placebo and active-controlled phase III study investigating oliceridine (TRV130), a G protein-biased ligand at the &micro;-opioid receptor, for management of moderate-to-severe acute pain following bunionectomy</p>
14天前
已完结
A randomized, phase 2 study investigating TRV130, a biased ligand of the μ-opioid receptor, for the intravenous treatment of acute pain
14天前
已完结
Biased agonism of the μ-opioid receptor by TRV130 increases analgesia and reduces on-target adverse effects versus morphine: A randomized, double-blind, placebo-controlled, crossover study in healthy volunteers
14天前
已完结
Design, synthesis and biological evaluation of novel analgesic agents targeting both cyclooxygenase and TRPV1
16天前
已完结
Antisense oligonucleotides selectively suppress target RNA in nociceptive neurons of the pain system and can ameliorate mechanical pain
17天前
已完结
TRPA1 siRNA-Loaded Nanoformulation Ameliorates Chemotherapy-Induced Peripheral Neuropathy
18天前
已完结
Effect of intrathecal NIS-lncRNA antisense oligonucleotides on neuropathic pain caused by nerve trauma, chemotherapy, or diabetes mellitus
18天前
已完结
Rational Design of Helical Peptoids for Tetracycline Conjugation: Insights into Molecular Complexation Mechanisms
1个月前
已关闭
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