Lv3
290 积分 2025-04-07 加入
Discovery of Atirmociclib (PF-07220060): A Potent and Selective CDK4 Inhibitor
1个月前
已完结
A Three-Step Method for the Preparation of N-Substituted 3,4-Dihydroisoquinolin-1(2H)-ones and Heteroaryl-Fused 3,4-Dihydropyridin-2(1H)-ones from 2-Bromobenzoate Precursors
2个月前
已完结
Discovery and Characterization of a First-In-Class HCK/BTK PROTAC DFCI-002-06 for the Treatment of MYD88 Mutated B Cell Malignancies
3个月前
已完结
Covalent inhibitors of the PI3Kα RAS binding domain impair tumor growth driven by RAS and HER2
6个月前
已完结
RAS Mutations in Advanced Colorectal Cancer: Mechanisms, Clinical Implications, and Novel Therapeutic Approaches
7个月前
已完结
Current developments in PI3K-based anticancer agents: Designing strategies, biological activity, selectivity, structure-activity correlation, and docking insight
7个月前
已完结
Advancements in dual-target inhibitors of PI3K for tumor therapy: Clinical progress, development strategies, prospects
7个月前
已完结
Recent advances in PI3K/PKB/mTOR inhibitors as new anticancer agents
7个月前
已完结
Phenotypic Screening for Targeted Protein Degradation: Strategies, Challenges, and Emerging Opportunities
8个月前
已完结
HER2 mediates clinical resistance to the KRASG12C inhibitor sotorasib, which is overcome by co-targeting SHP2
8个月前
已完结
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