Lv4
510 积分 2023-12-18 加入
Subtle Structural Modifications Spanning from EP4 Antagonism to EP2/EP4 Dual Antagonism: A Novel Class of Thienocyclic-Based Derivatives
15小时前
已完结
Discovery and Characterization of Benzamide Derivatives as Highly Potent SUCNR1 Antagonists for Cancer Immunotherapy
15小时前
已完结
From Hit to Lead: Discovery of Novel Selective RIPK1 Inhibitor with Pyridoimidazole Scaffold for the Treatment of Autoimmune Diseases through Phenotypic Screening and Structural Optimization
2个月前
已完结
Discovery of Novel Selective Dual Agonists Targeting S1PR1 and S1PR5 for the Treatment of Inflammatory Bowel Disease
2个月前
已完结
Development of the first-in-class RNF4 PROTAC degrader as potential therapeutics for hepatocellular carcinoma
2个月前
已完结
Identification of Benzofuro[2,3-b]pyridine Pseudonatural Product as a Novel Class of Ferritinophagy Inhibitors that Potently Suppress Ferroptosis
2个月前
已完结
Structure-based development of potent and selective type-II kinase inhibitors of RIPK1
2个月前
已完结
Identification of a Selective YTHDF1 Inhibitor Targeting the m6A Recognition Domain for Breast Cancer
2个月前
已完结
Discovery of Novel 5,6-Dihydro-1,2,4-triazine Derivatives as Efficacious Glucagon-Like Peptide-1 Receptor Agonists
9个月前
已完结
A BACH1 Inhibitor Ameliorates Myocardial Infarction and Limb Ischemia in Mice
9个月前
已完结
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