Lv11
48 积分 2026-03-11 加入
Loss of ADAR1 in tumours overcomes resistance to immune checkpoint blockade
2小时前
已完结
Targeting ADAR1 with a Novel Small-Molecule for the Treatment of Prostate Cancer
3小时前
已完结
Impaired mitochondrial oxidative phosphorylation limits the self-renewal of T cells exposed to persistent antigen
24天前
已完结
Metabolic reprogramming of terminally exhausted CD8+ T cells by IL-10 enhances anti-tumor immunity
24天前
已完结
IL-2 regulates tumor-reactive CD8+ T cell exhaustion by activating the aryl hydrocarbon receptor
25天前
已完结
A novel chimeric antigen receptor containing a JAK–STAT signaling domain mediates superior antitumor effects
1个月前
已完结
IL-10-expressing CAR T cells resist dysfunction and mediate durable clearance of solid tumors and metastases
1个月前
已完结
Constitutive STAT3 signaling, in comparison to STAT5, enhances CAR T cell efficacy and lowers systemic toxicity
1个月前
已完结
Discovery of Tetracyclic Derivatives as Highly Potent, Selective, and Bioavailable PKMYT1 Inhibitors for Cancer Therapy
1个月前
已完结
Interleukin-2 Activity Can Be Fine Tuned with Engineered Receptor Signaling Clamps
2个月前
已完结
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