Lv5
1100 积分 2022-06-29 加入
In vitro evaluation of 9-(2-phosphonylmethoxyethyl)adenine ester analogues, a series of anti-HBV structures with improved plasma stability and liver release
6天前
已完结
Synthesis and in Vivo Evaluation of Prodrugs of 9-[2-(Phosphonomethoxy)ethoxy]adenine
6天前
已完结
Expanding the binding space of argonaute-2: incorporation of either E or Z isomers of 6′-vinylphosphonate at the 5′ end of the antisense strand improves RNAi activity
1个月前
已完结
Exploring the potential of structural modeling and molecular docking for efficient siRNA screening: A promising approach to Combat viral mutants, with a focus on HIV-1
1个月前
已完结
Spatially Confined Intervention of Cellular Senescence by a Lysosomal Metabolism Targeting Molecular Prodrug for Broad‐Spectrum Senotherapy
1个月前
已完结
Safety and efficacy of the oral TLR8 agonist selgantolimod in individuals with chronic hepatitis B under viral suppression
1个月前
已完结
In vivo endosomal escape assay identifies mechanisms for efficient hepatic LNP delivery
1个月前
已完结
Generation and Characterization of Iduronidase-Cleavable ADCs
1个月前
已完结
Inhibitory Effects on RNA Binding and RNase H Induction Activity of Prodrug-Type Oligodeoxynucleotides Modified with a Galactosylated Self-Immolative Linker Cleavable by β-Galactosidase
2个月前
已完结
Glycosidase-targeting small molecules for biological and therapeutic applications
2个月前
已完结
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