Lv51
1480 积分 2022-08-08 加入
Discovery of a Natural Ent-Kaurene Diterpenoid Oridonin as an E3 Ligase Recruiter for PROTACs
4天前
已完结
Bcl11a maintains hematopoietic stem cell function but accelerates inflammation-driven exhaustion during aging
10天前
已完结
PD-L1 expression by dendritic cells is a key regulator of T-cell immunity in cancer
12天前
已完结
Discovery of Novel Proteolysis-Targeting Chimera Molecules as Degraders of Programmed Cell Death-Ligand 1 for Breast Cancer Therapy
13天前
已完结
An aging bone marrow exacerbates lung fibrosis by fueling profibrotic macrophage persistence
16天前
已完结
The gut microbiota–bile acid–TGR5 axis orchestrates platelet activation and atherothrombosis
17天前
已完结
A BCL-xL/BCL-2 PROTAC effectively clears senescent cells in the liver and reduces MASH-driven hepatocellular carcinoma in mice
19天前
已完结
Structure‐guided development of chemically tailored peptide binders of RNF43/ZNRF3 to enable versatile design of membrane protein‐targeting PROTACs
21天前
已完结
Niche-derived Semaphorin 4A safeguards functional identity of myeloid-biased hematopoietic stem cells
1个月前
已完结
Paracrine FGF21 dynamically modulates mTOR signaling to regulate thymus function across the lifespan
1个月前
已完结
Perioperative Neurocognitive Disorder: Reply
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