Lv3
394 积分 2024-05-24 加入
Human Urine-Derived SIX2-Positive Renal Progenitor Cells Partially Improve Kidney Fibrosis by Paracrine Signaling
13天前
已完结
Intraperitoneal LPS or Poly(I:C) injection and monitoring of mice v1
28天前
已完结
BGB-45035, a selective IRAK4 CDAC, demonstrated fast IRAK4 degradation and strong signaling inhibition, and superior efficacy in preclinical disease models 2529
1个月前
已完结
Development of APH003─a Highly Potent, Selective, and Orally Bioavailable IRAK4 PROTAC Degrader for the Treatment of Inflammatory Diseases
1个月前
已完结
Induction of endotoxin tolerance in vivo inhibits activation of IRAK4 and increases negative regulators IRAK-M, SHIP-1, and A20
1个月前
已完结
A small molecule potent IRAK4 inhibitor abrogates lipopolysaccharide-induced macrophage inflammation in-vitro and in-vivo
1个月前
已完结
Altered thymic T-cell selection due to a mutation of the ZAP-70 gene causes autoimmune arthritis in mice
1个月前
已完结
A cereblon-based glue degrader of NEK7 regulates NLRP3 inflammasome in a context-dependent manner
2个月前
已完结
Anemoside B4 targets NEK7 to inhibit NLRP3 inflammasome activation and alleviate MSU-induced acute gouty arthritis by modulating the NF-κB signaling pathway
2个月前
已完结
Improvement in affinity and thermostability of a fully human antibody against interleukin-17A by yeast-display technology and CDR grafting
2个月前
已完结