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48 积分 2024-06-20 加入
CNS-PENETRANT NLRP3 INHIBITOR ACHIEVES DURABLE WEIGHT LOSS AND REVERSES HYPOTHALAMIC INFLAMMATION IN DIET-INDUCED OBESITY
23天前
已完结
NLRP3 inflammasome in sepsis (Review)
24天前
已完结
Ofirnoflast: A First-in-Class NEK7-Targeted Inhibitor of the NLRP3 Inflammasome
1个月前
已完结
Inflammation and resolution in obesity
1个月前
已完结
Safety, Tolerability, Pharmacokinetics, and Target Engagement of Single and Multiple Ascending Doses of Intravenous AZD4144, a Small Molecule NLRP3 Inhibitor for Treatment of AKI
1个月前
已关闭
A novel selective NLRP3 inhibitor shows disease-modifying potential in animal models of Parkinson’s disease
1个月前
已完结
Discovery of Clinical Candidate NT-0796, a Brain-Penetrant and Highly Potent NLRP3 Inflammasome Inhibitor for Neuroinflammatory Disorders
1个月前
已完结
A phase 2, proof-of-concept, placebo-controlled, randomized, multicenter, double-blind study to evaluate the efficacy, safety, tolerability, pharmacokinetics, and pharmacodynamics of Usnoflast (ZYIL1) in patients with amyotrophic lateral sclerosis
3个月前
已完结
Anti‐Neuroinflammatory and Anti‐Inflammatory Effects of the NLRP3 Inhibitor NT‐0796 in Subjects with Parkinson's Disease
3个月前
已完结
Anwulignan Alleviates IRI by the Activation of Nrf2/HO-1 Signaling Pathway and Inhibiting NLRP3-Caspase-1-GSDMD-Mediated Pyroptosis in Rats
6个月前
已完结
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