Lv1
40 积分 2025-04-08 加入
Diuretics. 3-Amino- and 3-hydroxy-7-chloro-3,4-dihydro-4-oxo-6-quinazolinesulfonamides
3天前
已完结
Overcoming Preclinical Safety Obstacles to Discover (S)-N-((1,2,3,5,6,7-Hexahydro-s-indacen-4-yl)carbamoyl)-6-(methylamino)-6,7-dihydro-5H-pyrazolo[5,1-b][1,3]oxazine-3-sulfonamide (GDC-2394): A Potent and Selective NLRP3 Inhibitor
1个月前
已完结
Discovery of Selective Histone Deacetylase 6 Inhibitors Using the Quinazoline as the Cap for the Treatment of Cancer
1个月前
已完结
Inhibiting RhoA Activation via GDP-state Stabilization to Relieve Heart Failure
1个月前
已完结
I2-Mediated Oxidative C–O Bond Formation for the Synthesis of 1,3,4-Oxadiazoles from Aldehydes and Hydrazides
1个月前
已完结
Degrading the key component of the inflammasome: development of an NLRP3 PROTAC
4个月前
已完结
Fragment-Based Screening of NSD2-PWWP1 Identifies Novel Covalent Allosteric Ligands That Diminish Methyllysine and DNA Binding Abilities of NSD2
4个月前
已完结
Discovery of a Highly Potent and Selective Inhibitor Targeting Protein Lysine Methyltransferase NSD2
4个月前
已完结
Ganoderic Acid A Modulates Enteric Neurons and Intestinal Homeostasis in Irritable Bowel Syndrome by Microbiota Sensing
4个月前
已完结
Trimeric natural products: structural diversity, biosynthesis, bioactivities and chemical synthesis
4个月前
已完结
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