Lv2
120 积分 2025-05-27 加入
Macrocyclization as a Source of Desired Polypharmacology. Discovery of Triple PI3K/mTOR/PIM Inhibitors
29天前
已完结
Discovery of KIN-8741, a Highly Selective Type IIb c-Met Kinase Inhibitor with Broad Mutation Coverage and Quality Drug-Like Properties for the Treatment of Cancer
1个月前
已完结
Targeting MET: Discovery of Small Molecule Inhibitors as Non-Small Cell Lung Cancer Therapy
1个月前
已完结
Discovery of BMS-986458, a Potent and Selective B-Cell Lymphoma 6 Protein Ligand-Directed Degrader, for the Treatment of B-Cell Non-Hodgkin Lymphoma
1个月前
已完结
Lessons learned in linking PROTACs from discovery to the clinic
1个月前
已完结
Valine-Alanine-Based Peptidomimetic Linker for Antibody-Drug Conjugates
1个月前
已完结
Discovery of Paltusotine (CRN00808), a Potent, Selective, and Orally Bioavailable Non-peptide SST2 Agonist
1个月前
已完结
Discovery of AZD9750, an Orally Bioavailable Androgen Receptor Degrader for the Treatment of Prostate Cancer
2个月前
已完结
Design and Synthesis of Novel Dual Fluoro-Substituted 10,11-Methylenedioxy-pyrrolo[3,4- b ]quinoline Alkaloid Analogs as Topo I/DDX5 Inhibitors for Colorectal Cancer
2个月前
已完结
Discovery of (3 R ,4 R )-15: An Advanced Factor B Inhibitor Entering Phase 3 for Complement-Mediated Diseases
2个月前
已完结
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