Lv1
98 积分 2025-02-21 加入
Novel CRBN-Recruiting Proteolysis-Targeting Chimeras as Degraders of Stimulator of Interferon Genes with In Vivo Anti-Inflammatory Efficacy
6小时前
已完结
A Dual-Target and Dual-Mechanism Design Strategy by Combining Inhibition and Degradation Together
3个月前
已完结
Discovery of an Orally Bioavailable STING Inhibitor with In Vivo Anti-Inflammatory Activity in Mice with STING-Mediated Inflammation
3个月前
已完结
Discovery of Potent and Selective FABP4/5 Inhibitors with an Isoquinolone Scaffold as Potential Therapeutics for Inflammation-Related Diseases
3个月前
已完结
JAK inhibition in STING-associated interferonopathy
4个月前
已完结
Familial chilblain lupus due to a gain-of-function mutation in STING
4个月前
已完结
Molecular mechanisms and cellular functions of cGAS–STING signalling
5个月前
已完结
Rational Design of CDK12/13 and BRD4 Molecular Glue Degraders
5个月前
已完结
An orally available non-nucleotide STING agonist with antitumor activity
6个月前
已完结
Discovery of Potent STING Inhibitors Bearing a Difluorobenzodioxol Structural Motif as Potent Anti-Inflammatory Agents
6个月前
已完结
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