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146 积分 2024-04-06 加入
A Dichloropropionamide-Substituted Diaminopyrimidine EGFR-TKI Overcomes Osimertinib Resistance in NSCLC via Dual Anchoring at Ser797 and Met793
4小时前
待确认
Discovery of Potent and Selective Pyrrolo[2,3-d]pyrimidine Derivatives as Fourth-Generation EGFR Inhibitors Targeting Triple Mutations
4小时前
已完结
Structural Analysis of the Macrocyclic Inhibitor BI‐4020 Binding to EGFR Kinase
5小时前
已完结
Crystal structures of PAK2 reveal new insights into its autoinhibitory mechanism
17小时前
已完结
Allosteric Inhibition of PKMYT1 Induces a Unique, Inactive ATP Binding Site Conformation
1天前
已完结
The Ubiquitin NMR Resource
1天前
已完结
Discovery of Small Molecule Ligands Targeting Orphan G Protein-Coupled Receptors GPR3, GPR6, and GPR12
1天前
已完结
Selectively targeting an inactive conformation of interleukin-2-inducible T-cell kinase by allosteric inhibitors
2天前
已完结
Crystal structures of PAK2 reveal new insights into its autoinhibitory mechanism
3天前
已完结
Discovery of Novel 1-Phenylpiperidine Urea-Containing Derivatives Inhibiting β-Catenin/BCL9 Interaction and Exerting Antitumor Efficacy through the Activation of Antigen Presentation of cDC1 Cells
6天前
已完结
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