Lv7
5000 积分 2021-05-25 加入
Discovery of Effective Dual PROTAC Degraders with Synergistic Antitumor Activity for Overcoming Tamoxifen-Resistant Breast Cancer
10天前
已完结
Induced proximity pushes beyond protein degraders, as first RIPTAC moves into the clinic
11天前
已完结
Antibody-drug conjugates against multidrug-resistant cancers: Biomarker-guided patient selection, payload engineering, linker chemistry, and bystander effects
21天前
已完结
Next-generation gemcitabine prodrugs: Overcoming biological barriers through chemical innovation
24天前
已完结
Linker Chemistry in Antibody–Drug Conjugates: Current Strategies, Clinical Pharmacokinetic Analyses, and Linker-Free Outlooks
24天前
已完结
Receptor-Targeted Folic Acid Ligand–Drug Conjugate of Exatecan Leads to Complete Tumor Regression in the Preclinical Tumor Model
29天前
已完结
Generative AI-Assisted Discovery of HPK1 Inhibitors
29天前
已完结
A Cathepsin B-Cleavable Self-Immolative Linker for the Delivery of Hydroxyl-Containing Payloads in Antibody–Drug Conjugates
1个月前
已完结
Process Development for the First GMP Synthesis of SGD-9501-TFA, Part 2: Synthesis of the Payload, Linker, and Drug Linker
1个月前
已完结
Process Development for the First GMP Synthesis of SGD-9501-TFA, Part 1: Synthesis of Two Oligopeptide Fragments
1个月前
已完结
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