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50 积分 2025-07-09 加入
The synthetic landscape of cereblon (CRBN) binders: from thalidomide to emerging chemotypes
22天前
已完结
The Role of Genetics in Malignant Melanoma
1个月前
已完结
GID4-Recruiting PROTACs for BRD4 Degradation Overcome Resistance Driven by CRBN and VHL Deficiency
1个月前
已完结
Development of hypoxia-activated PROTAC exerting a more potent effect in tumor hypoxia than in normoxia
1个月前
已完结
Targeting the cell-cycle machinery for cancer therapy
2个月前
已完结
Discovery of Artesunate (ARS) PROTACs as GPX4 protein degraders for the treatment of bladder cancer
3个月前
已完结
Targeting the von Hippel–Lindau E3 Ubiquitin Ligase Using Small Molecules To Disrupt the VHL/HIF-1α Interaction
3个月前
已完结
New PROTAC Designs for Targeted Protein Degradation in 2021–2025: Novel E3 Ligases and Pre-PROTACs
4个月前
已完结
Enriching Proteolysis Targeting Chimeras with a Second Modality: When Two Are Better Than One
4个月前
已完结
Phototriggered LYTAC: Photoactive Bispecific Aptamer Chimera Enhances Targeted Degradation of Membrane Protein through Regulating Cell Autophagy
5个月前
已完结
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