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46 积分 2025-07-09 加入
Discovery of Artesunate (ARS) PROTACs as GPX4 protein degraders for the treatment of bladder cancer
12小时前
待确认
Targeting the von Hippel–Lindau E3 Ubiquitin Ligase Using Small Molecules To Disrupt the VHL/HIF-1α Interaction
6天前
已完结
New PROTAC Designs for Targeted Protein Degradation in 2021–2025: Novel E3 Ligases and Pre-PROTACs
1个月前
已完结
Enriching Proteolysis Targeting Chimeras with a Second Modality: When Two Are Better Than One
1个月前
已完结
Phototriggered LYTAC: Photoactive Bispecific Aptamer Chimera Enhances Targeted Degradation of Membrane Protein through Regulating Cell Autophagy
1个月前
已完结
Bicyclic peptide-based CPPTACs for extracellular and cell membrane protein degradation
1个月前
已完结
Targeted degradation of cell surface proteins through endocytosis triggered by cell-penetrating peptide-small molecule conjugates
2个月前
已完结
Dual membrane receptor degradation via folate receptor targeting chimera
3个月前
已完结
Lessons learned in linking PROTACs from discovery to the clinic
3个月前
已完结
Development of Dual-Receptor Lysosome-Targeting Chimeras for Protein Degradation
6个月前
已完结