Lv11
42 积分 2025-07-09 加入
GID4-Recruiting PROTACs for BRD4 Degradation Overcome Resistance Driven by CRBN and VHL Deficiency
2小时前
已完结
Development of hypoxia-activated PROTAC exerting a more potent effect in tumor hypoxia than in normoxia
7天前
已完结
Targeting the cell-cycle machinery for cancer therapy
1个月前
已完结
Discovery of Artesunate (ARS) PROTACs as GPX4 protein degraders for the treatment of bladder cancer
1个月前
已完结
Targeting the von Hippel–Lindau E3 Ubiquitin Ligase Using Small Molecules To Disrupt the VHL/HIF-1α Interaction
2个月前
已完结
New PROTAC Designs for Targeted Protein Degradation in 2021–2025: Novel E3 Ligases and Pre-PROTACs
3个月前
已完结
Enriching Proteolysis Targeting Chimeras with a Second Modality: When Two Are Better Than One
3个月前
已完结
Phototriggered LYTAC: Photoactive Bispecific Aptamer Chimera Enhances Targeted Degradation of Membrane Protein through Regulating Cell Autophagy
3个月前
已完结
Bicyclic peptide-based CPPTACs for extracellular and cell membrane protein degradation
3个月前
已完结
Targeted degradation of cell surface proteins through endocytosis triggered by cell-penetrating peptide-small molecule conjugates
3个月前
已完结