Lv1
60 积分 2025-07-06 加入
The dTAG system for immediate and target-specific protein degradation
6个月前
已完结
IRE1α silences dsRNA to prevent taxane-induced pyroptosis in triple-negative breast cancer
8个月前
已完结
Discovery of the First-in-class DOT1L PROTAC Degrader
8个月前
已完结
Discovery of WDR5–MLL1 and HDAC Dual-Target Inhibitors for the Treatment of Acute Myeloid Leukemia
8个月前
已完结
Novel inhibitors of the histone methyltransferase DOT1L show potent antileukemic activity in patient-derived xenografts
8个月前
已完结
Complementary activities of DOT1L and Menin inhibitors in MLL-rearranged leukemia
8个月前
已完结
Structural insights into inhibition of the bivalent menin-MLL interaction by small molecules in leukemia
8个月前
已完结
Menin-MLL protein-protein interaction inhibitors: a patent review (2014–2021)
8个月前
已完结
Mechano-oncogenic cytoskeletal remodeling drives leukemic transformation with mitochondrial vesicle-mediated STING activation
9个月前
已完结
Taurine from tumour niche drives glycolysis to promote leukaemogenesis
9个月前
已完结
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