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72 积分 2026-07-08 加入
Insight into the Folding and Dimerization Mechanisms of the N-Terminal Domain from Human TDP-43
3天前
已完结
A single N‐terminal phosphomimic disrupts TDP‐43 polymerization, phase separation, and RNA splicing
3天前
已完结
Functional and dynamic polymerization of the ALS-linked protein TDP-43 antagonizes its pathologic aggregation
3天前
已完结
The era of cryptic exons: implications for ALS-FTD
23天前
已完结
Cryptic splicing in synaptic and membrane excitability genes links TDP-43 loss to neuronal dysfunction
24天前
已完结
Hydrogen–Deuterium Exchange Mass Spectrometry Reveals Mechanistic Insights into RNA Oligonucleotide-Mediated Inhibition of TDP-43 Aggregation
25天前
已完结
Patient-derived frontotemporal lobar degeneration brain extracts induce formation and spreading of TDP-43 pathology in vivo
25天前
已完结
Prion-like Properties of Pathological TDP-43 Aggregates from Diseased Brains
25天前
已完结
Autophagy induction enhances TDP43 turnover and survival in neuronal ALS models
25天前
已完结
Aberrant cleavage of TDP-43 enhances aggregation and cellular toxicity
25天前
已完结