Lv72
5000 积分 2021-05-11 加入
Quantitative Analysis of Inclisiran‐Oligonucleotide Therapy of Atherosclerotic Cardiovascular Disease Through Internal Standard‐Mediated Liquid Chromatography‐High‐Resolution Mass Spectrometry
1天前
已完结
Diastereomer Characterization of PS-Modified Synthetic Oligonucleotides Using Cyclic IMS-MS
2个月前
已完结
Real-Time Monitoring of Higher-Order Structure of RNAs by Temperature-Course Size Exclusion Chromatography and Microfluidic Modulation Spectroscopy
3个月前
已完结
Current CMC challenges in oligonucleotide API development: from IND to NDA
5个月前
已完结
Investigating TmMethod Specificity Using Oligonucleotide Sequence Variants
5个月前
已完结
A tiered approach to threshold of regulation
6个月前
已完结
Development of an ICP-MS/MS approach for absolute quantification and determination of phosphodiester to phosphorothioate ratio in therapeutic oligonucleotides
6个月前
已完结
Decoding diastereomeric and impurity profiles of phosphorothioated siRNAs via 2D anion-exchange chromatography coupled with ion-pair reversed phase liquid chromatography mass spectrometry
6个月前
已完结
Metabolically Stable Anomeric Linkages Containing GalNAc–siRNA Conjugates: An Interplay among ASGPR, Glycosidase, and RISC Pathways
6个月前
已完结
Process Development for Purification of Therapeutic Antisense Oligonucleotides by Anion-Exchange Chromatography
7个月前
已完结