Lv62
2010 积分 2023-05-08 加入
PCSK9 inhibition with orally administered NNC0385-0434 in hypercholesterolaemia: a randomised, double-blind, placebo-controlled and active-controlled phase 2 trial
1小时前
待确认
Discovery of Truncated Cyclic Peptides Targeting an Induced-Fit Pocket on PCSK9
1天前
待确认
The evolution of lipid-lowering drugs in the management of cardiovascular disease risk: From the first cardiovascular disease risk–reducing therapies to the novel challenging strategies
1天前
待确认
Discovery of novel and selective SIK2 inhibitors by the application of AlphaFold structures and generative models
14天前
已完结
Safety, clinical activity, pharmacodynamics, and pharmacokinetics of IMU-856, a SIRT6 modulator, in coeliac disease: a first-in-human, randomised, double-blind, placebo-controlled, phase 1 trial
15天前
已完结
Semaglutide ameliorates cognition and glucose metabolism dysfunction in the 3xTg mouse model of Alzheimer's disease via the GLP-1R/SIRT1/GLUT4 pathway
20天前
已完结
Tirzepatide shows neuroprotective effects via regulating brain glucose metabolism in APP/PS1 mice
20天前
已完结
Effects of Glucagon-like peptide 1 (GLP-1) analogs in the hippocampus
22天前
已完结
Glucagon-like peptide-1 analogs mitigate neuroinflammation in Alzheimer's disease by suppressing NLRP2 activation in astrocytes
22天前
已完结
Dual targeting of TNF and IL-23 by a bispecific antibody in ulcerative colitis
28天前
已关闭
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