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448 积分 2023-07-24 加入
A Review of Conjugation Technologies for Antibody Drug Conjugates
6小时前
已完结
Discovery of Potent and Selective Covalent Inhibitors of HER2WT and HER2YVMA
1天前
已完结
Discovery of potent and selective HER2 PROTAC degrader based Tucatinib with improved efficacy against HER2 positive cancers
2天前
已完结
Deep Learning‐Guided Molecular Docking for Rapid Identification of Novel HER2 Inhibitors in Breast Cancer Therapy
3天前
已完结
AYVM to AYMM transition on HER2 exon 20 insertion induces TKI resistance in NSCLC
3天前
已完结
Discovery of potent and selective HER2 inhibitors with efficacy against HER2 exon 20 insertion-driven tumors, which preserve wild-type EGFR signaling
3天前
已完结
Elimination of tucatinib, a small molecule kinase inhibitor of HER2, is primarily governed by CYP2C8 enantioselective oxidation of gem-dimethyl
3天前
已完结
Absorption, distribution, metabolism, and excretion of [14C]BYL719 (alpelisib) in healthy male volunteers
3天前
已完结
Hydrolysis of Phosphonothioates with a Binaphthyl Group: P-Stereogenic O-Binaphthyl Phosphonothioic Acids and Their Use as Optically Active Ligands and Chiral Discriminating Agents
3天前
已完结
Scope of Aminomethylations via Suzuki−Miyaura Cross-Coupling of Organotrifluoroborates
5天前
已完结
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