Lv11
4 积分 2026-05-12 加入
Discovery of a Novel Thienopyrimidine Derivative as a Potent Dual URAT1/GLUT9 Inhibitor with Enhanced Urate-Lowering Efficacy, Superior Pharmacokinetics, and Favorable Safety Profile for Gout and Hyperuricemia
5小时前
已完结
Discovery and Optimization of 6-Azaindole URAT1 Inhibitors to Address Kidney and Liver Related Toxicities
5小时前
已完结
Rational Design of Azaindole Derivatives via a Nitrogen-Walk Strategy from β-Carboline: Discovery of Highly Selective, Low-Toxicity URAT1 Inhibitors as Potent Urate-Lowering Agents
5小时前
已完结
Discovery of FLT3-ITD Inhibitor Clifutinib: A Novel Biphenylacetylene Urea Derivative in Clinical Trials for the Treatment of Relapsed/Refractory FLT3-ITD+ Acute Myeloid Leukemia
2个月前
已完结
Discovery of Potent Dual PROTAC Degraders Targeting BET-Kinase To Overcome FLT3 Inhibitor Resistance
2个月前
已完结
Discovery of Imidazo[2,1- b ][1,3,4]thiadiazole-Based MNK Inhibitors with Anti-inflammatory Efficacy via Dual Suppression of eIF4E Phosphorylation and NF-κB Signaling
4个月前
已完结
Drugs for Sexually Transmitted Infections
5个月前
已关闭
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