Lv44
658 积分 2026-05-19 加入
Intersystem Extrapolation Factors Are Substrate-Dependent for CYP3A4: Impact on Cytochrome P450 Reaction Phenotyping
29天前
已完结
Orforglipron, an Oral Small-Molecule GLP-1 Receptor Agonist for Obesity Treatment
1个月前
已完结
767-P: A Phase 1b/2a Study of the Safety and Tolerability of GSBR-1290, a Novel Oral Small Molecule Glucagon-Like Peptide 1 Receptor Agonist (GLP-1RA), in Healthy Overweight/Obese Volunteers (HOV) and Participants with Type 2 Diabetes Mellitus (T2DM)
1个月前
已完结
Once‐daily oral small‐molecule glucagon‐like peptide‐1 receptor agonist lotiglipron (PF‐07081532) for type 2 diabetes and obesity: Two randomized, placebo‐controlled, multiple‐ascending‐dose Phase 1 studies
1个月前
已完结
Investigation of the suitability of utilizing plasma concentration as a surrogate to understand lung exposure of inhaled drug in rats: Different delivery methods of fluticasone propionate
1个月前
已完结
Practical and Scalable Method for Manufacturing AZD4604, A Potent and Selective JAK1 Inhibitor
1个月前
已完结
Discovery of the Potent and Selective Inhaled Janus Kinase 1 Inhibitor AZD4604 and Its Preclinical Characterization
1个月前
已完结
Characterization of T-5 N-Oxide Formation as the First Highly Selective Measure of CYP3A5 Activity
1个月前
已完结
In vitro metabolism of simvastatin in humans [SBT]identification of metabolizing enzymes and effect of the drug on hepatic P450s
1个月前
已关闭
Comparison of Commonly Used and New Methods to Determine Small Molecule Non-Specific Binding to Human Liver Microsomes
1个月前
已完结