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860 积分 2025-07-28 加入
Impact of Nuclear De Novo NAD + Synthesis via Histone Dynamics on DNA Repair during Cellular Senescence To Prevent Tumorigenesis
6天前
已完结
Nicotinic acid riboside maintains NAD+ homeostasis and ameliorates aging-associated NAD+ decline
6天前
已完结
The cGAS–STING, p38 MAPK, and p53 pathways link genome instability to accelerated cellular senescence in ATM-deficient murine lung fibroblasts
17天前
已完结
Mitochondrial fatty acid oxidation drives senescence
17天前
已完结
DNA damage‐induced cellular senescence is regulated by 53BP1 accumulation in the nuclear foci and phase separation
17天前
已完结
Mechanism of DNA replication fork breakage and PARP1 hyperactivation during replication catastrophe
17天前
已完结
Discovery of a new hereditary RECQ helicase disorder RECON syndrome positions the replication stress response and genome homeostasis as centrally important processes in aging and age-related disease
18天前
已完结
The loss of heterochromatin is associated with multiscale three-dimensional genome reorganization and aberrant transcription during cellular senescence
21天前
已完结
cGAS-STING targeting offers novel therapeutic opportunities in neurological diseases
21天前
已完结
Pathophysiological Roles of the cGAS-STING Inflammatory Pathway
21天前
已完结
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