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50 积分 2021-03-11 加入
Designing Chromane Derivatives as α2A-Adrenoceptor Selective Agonists via Conformation Constraint
22天前
已完结
Rational modification of PROTACs for tumor-selective protein degradation
26天前
已完结
Enrichment-Free, Targeted Covalent Drug Discovery in Live Cells
1个月前
已完结
VIPER-TACs leverage viral E3 ligases for disease-specific targeted protein degradation
1个月前
已完结
Discovery of Novel Potent Triple IKZF1/2/3 Degraders for the Treatment of Hematological Cancers
1个月前
已完结
Identification of an allosteric site on the E3 ligase adapter cereblon
1个月前
已完结
Targeted clearance of mitochondria by an autophagy-tethering compound (ATTEC) and its potential therapeutic effects
2个月前
已完结
A Degron Blocking Strategy Towards Improved CRL4CRBN Recruiting PROTAC Selectivity**
2个月前
已完结
Structural basis of lenalidomide-induced CK1α degradation by the CRL4CRBN ubiquitin ligase
2个月前
已完结
Structure of the human Cereblon–DDB1–lenalidomide complex reveals basis for responsiveness to thalidomide analogs
2个月前
已完结
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