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The Discovery of TNG456: A Highly Potent, Selective, Brain-Penetrant MTA-Cooperative PRMT5 Inhibitor for the Treatment of MTAP -Deleted Cancers
1个月前
已完结
Structure, Function, and Activity of Small Molecule and Peptide Inhibitors of Protein Arginine Methyltransferase 1
2个月前
已完结
Protein Arginine Methyltransferase 8: Tetrameric Structure and Protein Substrate Specificity
2个月前
已完结
Crystal structure of full-length human PRMT8 reveals helical octamer assembly required for membrane localization and catalytic activity
2个月前
已完结
Activity and Function of the PRMT8 Protein Arginine Methyltransferase in Neurons
2个月前
已完结
Aryl Pyrazoles as Potent Inhibitors of Arginine Methyltransferases: Identification of the First PRMT6 Tool Compound
2个月前
已完结
Discovery of a First-in-Class Protein Arginine Methyltransferase 6 (PRMT6) Covalent Inhibitor
2个月前
已完结
Pharmacophore-based screening of diamidine small molecule inhibitors for protein arginine methyltransferases
2个月前
已完结
Activity and Function of the PRMT8 Protein Arginine Methyltransferase in Neurons
2个月前
已完结
A patent review of arginine methyltransferase inhibitors (2010–2018)
2个月前
已完结