Lv11
50 积分 2023-11-07 加入
Selective degradation of splicing factor CAPERα by anticancer sulfonamides
3小时前
待确认
Anticancer sulfonamides target splicing by inducing RBM39 degradation via recruitment to DCAF15
3小时前
已完结
Discovery and Optimization of the First ATP Competitive Type-III c-MET Inhibitor
8天前
已完结
Emerging MET tyrosine kinase inhibitors for the treatment of non-small cell lung cancer
12天前
已完结
Covalent Recruitment of NEDD4 for Targeted Protein Degradation: Rational Design of Small Molecular Degraders
24天前
已完结
Integrative Modeling of PROTAC-Mediated Ternary Complexes
1个月前
已完结
Acquired Resistance to KRASG12C Inhibition in Cancer
2个月前
已完结
Discovery of Novel Potent Triple IKZF1/2/3 Degraders for the Treatment of Hematological Cancers
2个月前
已完结
Rational design of VHL-recruiting KRASG12C proteolysis-targeting chimeras based on molecular dynamics simulation
3个月前
已完结
Small-molecule hydrophobic tagging–induced degradation of HaloTag fusion proteins
4个月前
已完结