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128 积分 2021-02-02 加入
Generating Surprisingly Powerful Pharmacology from Chemically Induced Protein Interactions
18天前
已完结
Loss of APJ mediated β-arrestin signalling improves high-fat diet induced metabolic dysfunction but does not alter cardiac function in mice
3个月前
已完结
Safety considerations for cereblon-recruiting targeted protein degraders
3个月前
已完结
Smallest Bicycles in Medicinal Chemistry: Where Are We Now?
3个月前
已完结
Discovery of Small-Molecule GLP-1 Receptor Agonists with Improved Oral Pharmacokinetics Based on Orforglipron
3个月前
已完结
NN1213 – A Potent, Long-Acting, and Selective Analog of Human Amylin
4个月前
已完结
Rational Design of Potent and Orally Efficacious PI3Kα/δ Degrader for PIK3CA Mutant Breast Cancer without Hyperglycemic Liability
4个月前
已完结
Ringing medicinal chemistry: The importance of 3-membered rings in drug discovery
4个月前
已完结
Evaluation of Oral PROTAC Guidelines: Efflux Ratio Outweighs Chameleonicity Descriptors
5个月前
已完结
Ring Systems in Medicinal Chemistry: A Cheminformatics Analysis of Ring Popularity in Drug Discovery Over Time
5个月前
已完结
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