Lv1
26 积分 2026-05-14 加入
Discovery of Daraxonrasib (RMC-6236), a Potent and Orally Bioavailable RAS(ON) Multi-selective, Noncovalent Tri-complex Inhibitor for the Treatment of Patients with Multiple RAS-Addicted Cancers
10天前
已完结
Developing Predictive Models by Sharing Predictions – An Investigation of a Federated Learning Approach for ADMET Predictions
1个月前
已完结
Design, Synthesis, and Biological Evaluation of Novel Diaminopyrimidine Macrocycles as Fourth Generation Reversible EGFR Inhibitors That Overcome Clinical Resistance to Osimertinib Mediated by C797S Mutation
1个月前
已完结
A Self-Assembled Nano-Molecular Glue (Nano-mGlu) Enables GSH/H2O2-Triggered Targeted Protein Degradation in Cancer Therapy
1个月前
已完结
Flow matching for generative modeling in bioinformatics and computational biology
1个月前
已完结
Selective and Potent Molecular Glue Degraders for NIMA‐Related Kinase 7
1个月前
已完结
Calibrated geometric deep learning improves kinase–drug binding predictions
1个月前
已完结
Design, Synthesis, and Biological Evaluation of the First Novel Macrocycle-Based FGFR Inhibitors That Overcome Clinically Acquired Resistance
1个月前
已完结
Broadening the molecular glue landscape
2个月前
已完结
A highly selective and orally bioavailable casein kinase 1 alpha degrader through p53 signaling pathway targets B-cell lymphoma cells
2个月前
已完结
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