Lv11
60 积分 2026-05-26 加入
Functional and targeted proteomics characterization of a human primary endothelial cell model of the blood-brain barrier (BBB) for drug permeability studies
22分钟前
待确认
ABCB1 limits brain exposure of the KRASG12C inhibitor sotorasib, whereas ABCB1, CYP3A, and possibly OATP1a/1b restrict its oral availability
1小时前
已完结
Efficacy and safety of the muscarinic receptor agonist KarXT (xanomeline–trospium) in schizophrenia (EMERGENT-2) in the USA: results from a randomised, double-blind, placebo-controlled, flexible-dose phase 3 trial
2天前
已完结
Brain and Blood Biomarkers of Major Depressive Disorder
3天前
已完结
Surrogate Light Chain Expressing Human Peripheral B Cells Produce Self-reactive Antibodies
28天前
已关闭
Plasma Pharmacokinetics of High-Affinity Transferrin Receptor Antibody-Erythropoietin Fusion Protein is a Function of Effector Attenuation in Mice
1个月前
已完结
How predictive are in vitro assays for cytokine release syndrome in vivo? A comparison of methods reveals worrying differences in sensitivity and frequency of response
1个月前
已关闭
A whole blood in vitro cytokine release assay with aqueous monoclonal antibody presentation for the prediction of therapeutic protein induced cytokine release syndrome in humans
1个月前
已完结
Recent Advances in Delivery of Peptide and Protein Therapeutics to the Brain
2个月前
已完结
Schisandrin A ameliorates increased pulmonary capillary endothelial permeability accompanied with sepsis through inhibition of RhoA/ROCK1/MLC pathways
2个月前
已完结