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638 积分 2023-02-06 加入
MRGPRX2 Antagonist Treatment Prevents Inflammation and Disease in a Mouse Model of Atopic Dermatitis
4天前
已完结
Macropinocytosis-mediated recyclable LYTACs (McR-TACs) for receptor-independent protein degradation
8天前
已完结
Discovery and characterization of pyridazino[4,5-b]indol-4-one derivatives as NaV1.8 inhibitors: A novel approach for targeting chronic pain
18天前
已完结
Modular Access to Diverse Soluble Epoxide Hydrolase Degraders as Potential Agents for Alleviating LPS-Induced Acute Inflammation
1个月前
已完结
Induced proximity-based therapeutic modalities
1个月前
已完结
Enabling formulations for PROTACs: A line-of-sight to clinic
2个月前
已完结
Enabling formulations for PROTACs: A line-of-sight to clinic
2个月前
已关闭
Discovery and Characterization of a New Class of C5aR1 Antagonists Showing In Vivo Activity
2个月前
已完结
Scalable Synthesis of C5aR1 Antagonist ACT-1014-6470 via N7-Selective Reductive Amination of an Unprotected Pyrazole Starting Material and Intramolecular Urea Formation with 1,1′-Carbonyl-di(1,2,4-triazol) (CDT)
2个月前
已完结
Identification of Clofibric Acid as a Synoviolin (SYVN1) Ligand for Proteolysis-Targeting Chimera (PROTAC) Development
3个月前
已完结
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