Lv11
90 积分 2025-10-11 加入
Discovery of 4-Amino-8-quinoline Carboxamides as Novel, Submicromolar Inhibitors of NAD-Hydrolyzing Enzyme CD38
1小时前
已完结
Nicotinamide Riboside and CD38: Covalent Inhibition and Live-Cell Labeling
7天前
已完结
Uncompetitive, adduct-forming SARM1 inhibitors are neuroprotective in preclinical models of nerve injury and disease
7天前
已完结
A Covalent Binding Mode of a Pyrazole‐Based CD38 Inhibitor
7天前
已完结
Autophagy and beyond: Unraveling the complexity of UNC-51-like kinase 1 (ULK1) from biological functions to therapeutic implications
1个月前
已完结
Structure of the Human Autophagy Initiating Kinase ULK1 in Complex with Potent Inhibitors
1个月前
已完结
Discovery and structure of a new inhibitor scaffold of the autophagy initiating kinase ULK1
1个月前
已完结
Conservation of structure, function and inhibitor binding in UNC-51-like kinase 1 and 2 (ULK1/2)
1个月前
已完结
Development of potent and selective ULK1/2 inhibitors based on 7-azaindole scaffold with favorable in vivo properties
1个月前
已完结
Probing the Protein Kinases′ Cysteinome by Covalent Fragments
1个月前
已完结
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